| ncRNA name | YAP siRNA |
| ncRNA Category | siRNA |
| Disease name | choroidal neovascularization (CNV) |
| Species | Mus musculus |
| Tissues/Cell_line | RPE-choroid-sclera complexes and retinas |
| Methods | Western blot, immunohistochemistry, siRNA injection, fundus fluorescein angiography, H&E staining, immunofluorescent double staining |
| Expression pattern | associated |
| Functional description | YAP siRNA and ranibizumab decreased VEGF expression and the incidence and leakage area of CNV. After laser exposure, YAP siRNA inhibited the increased expression of PCNA, which was colocalized with endothelial cells. |
| PubMed ID | 29422766 |
| Year | 2018 |
| Title | Inhibition of YAP ameliorates choroidal neovascularization via inhibiting endothelial cell proliferation. |
| Drug-related ncRNA | NO |
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